Synthesis of 3-amino-2-alkenoate

نویسندگان

  • Albert Chen
  • Mohammad Movassaghi
  • Robert Sindelar
چکیده

The main aim of the project is to synthesize an isomerically pure sample of 3-amino-2alkenoate, a useful β-amino acid derivative that is a precursor to molecules with medicinal properties. We successfully made the product from the reaction of ethyl acetoacetate and ammonium acetate dissolved in methanol. We also attempted to synthesize 3-pyrrole-2alkenoate from the reaction of our product and 2,5-dimethoxytetrahydrofuran. The products of both reactions were chracterized by means of H nuclear magnetic resonance spectroscopy.

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تاریخ انتشار 2007